Linezolid in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis in paediatric patients: Experience of a paediatric infectious diseases unit

Abstract

Linezolid has been used in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis in adults with encouraging results, however experience in children is scarce. We describe our experience with the use of linezolid as part of a multidrug regimen in the treatment of 4 patients who had persistent positive cultures, despite prolonged combined therapy.

Keywords::

• Linezolid
• tuberculosis
• multidrug-resistant
• extensively drug-resistant
• paediatric

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.