Evidence of simian virus 40 infection in multiple organ transplant recipients with renal dysfunction

Abstract

Electron microscopy (EM), real-time polymerase chain reaction (PCR) and conventional PCR were used to identify viruses associated with infection in 2 transplantation patients. An autologous haematopoietic stem cell, liver and renal transplant recipient was found to be positive for simian virus 40 (SV40). Dual BK virus and SV40 infection was found in a heart and renal transplantation patient. SV40 infection can occur in immunocompromised patients.

Keywords::

• Polyomavirus
• SV40
• PCR
• real-time PCR
• transplantation patients
• renal dysfunction

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.