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Scandinavian Journal of Infectious Diseases Volume 45, 2013 - Issue 10
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CASE REPORTS

Neonatal transfusion-transmitted hepatitis C virus infection following a pre-seroconversion window-phase donation in Sweden

Jesper Waldenström From the Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg
,
Jan KonarDepartment of Transfusion Medicine, Sahlgrenska University Hospital, Gothenburg
,
Bengt EkermoDepartment of Clinical Immunology and Transfusion Medicine, County Council of Östergötland, Linköping University, Sweden
,
Helene Norder From the Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg
&
Martin Lagging From the Department of Infectious Diseases/Virology, Institute of Biomedicine, Sahlgrenska Academy, University of GothenburgCorrespondence[email protected]
Pages 796-799 | Received 02 Apr 2013, Accepted 10 Apr 2013, Published online: 09 Jun 2013
 
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Abstract

A 9-day-old child developed a transfusion-transmitted hepatitis C virus (HCV) infection following a pre-seroconversion window-phase donation. Retrospective analysis of donor plasma revealed detectable HCV core antigen (154 fmol/l), as well as HCV RNA (87,000 IU/ml). Of 5.24 million Swedish plasma samples from December 1998 to September 2012, 5 additional window-phase donations were identified.

Declaration of interest: None of the authors have any conflict of interest.

This study was supported by The Swedish Medical Research Council (grant 2011-3821) and ALF Funds (grant ALFGBG-3149).

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