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Ultrastructural Pathology Volume 15, 1991 - Issue 4-5
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Original Article

Oncocytic Adrenal Cortical Carcinoma

Adel K. El-Naggar Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, 77030, USA
,
Douglas B. Evans Department of Surgery, University of Texas M. D. Anderson Cancer Center, Houston, Texas, 77030, USA
&
Bruce Mackay Department of Surgery, University of Texas M. D. Anderson Cancer Center, Houston, Texas, 77030, USA
Pages 549-556 | Published online: 10 Jul 2009
 
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Abstract

A case of adrenal cortical carcinoma composed of mitochondria-rich cells is reported. The cells contained condensed zones and loose whorls of smooth endoplasmic reticulum. Crystalline matrical inclusions were present in some of the mitochondria, whereas others contained round, homogeneous, dense matrical inclusions. Flow cytometry revealed a hyperdiploid stem line with a DNA index of 1.3.

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