Abstract
Multiple treatments may be used in the management of patients with brain metastases including surgical resection or radiosurgery. In order to determine whether initial surgical resection in any way prejudices the subsequent efficacy of radiosurgery for recurrence at the operated site, a retrospective review of patients undergoing radiosurgery at the time of relapse was undertaken. All patients had previously received whole brain irradiation as part of initial management. A comparison of radiosurgical planning technique was made for recurrent brain metastases occurring at sites of a previous surgical resection versus unresected recurrences. Although recurrences of tumour at a resected site were more likely to be treated radiosurgically using larger and multiple collimators, there was no significant difference in subsequent local control. Assuming that the recurrence of a brain metastasis at a previously resected site is considered treatable radiosurgically, subsequent local control is no different from that achieved in previously unresected recurrences.
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.