A retrospective study of heterogeneity in neurocognitive profiles associated with traumatic brain injury

Abstract

Primary objective: To establish empirical sub-types, based upon cognitive test results of individuals who had sustained traumatic brain injury.

Research design: The study was retrospective, applying cluster analyses and associated statistical tests to an established database.

Methods and procedures: Neuropsychological data from veterans with brain trauma were cluster analysed using the WAIS-R and Halstead-Reitan Battery (HRB). External validity of the cluster solutions was evaluated.

Experimental interventions: The study was based upon use of an established database that contained cognitive test data and information regarding diagnosis and clinical history.

Main outcomes and results: The WAIS-R clusters described sub-groups with near normal function, preserved verbal but impaired problem-solving abilities or global impairment. The HRB clusters differed in level of performance with Near Normal, Moderately Impaired and Globally Impaired clusters. Cluster membership was associated with age and employment status, but not with neurological findings.

Conclusion: The outcome of traumatic brain injury is heterogeneous and mainly associated with demographic considerations.

• Brain injury
• assessment
• cluster analysis
• intelligence

Acknowledgements

This research was supported by the DVA VISN IV Mental Illness Research, Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA and the Medical Research Service, Department of Veterans Affairs.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.