A Family with the 619 bp Deletion on the β-globin Gene Found in Kerman Province, Iran

Abstract

In the present study, we report the first case of a 619 bp deletion on the β-globin gene, found in a family from Kerman Province, Iran. This mutation is frequent in Pakistan, but it has not been previously reported in any part of Iran. This study revealed that all family members have this β⁰-thalassemia (β⁰-thal) mutation.

Keywords:

• 619 bp Deletion
• β-Globin gene
• β-Thalassemia (β-thal)

ACKNOWLEDGMENTS

We thank Dr. Anuradha Kumari (Oregon Health and Science University, Portland, OR, USA), and Dr. Ali-Akbar Haghdoost (Kerman University of Medical Sciences, Kerman, Iran) for editing this article. Thanks are also due to Afzalipour Hospital, Kerman, Iran for financially supporting this study and to the Jiroft Health Services, Jiroft, Kerman Province, Iran for their helpful data.

Declaration of Interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.