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Hemoglobin
international journal for hemoglobin research
Volume 33, 2009 - Issue sup1
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PROCEEDINGS OF THE 1ST PAN-MIDDLE EASTERN CONFERENCE ON HAEMOGLOBINOPATHIES DAMASCUS (SYRIA), 1–2 MAY, 2009 GUEST EDITORS: MICHAEL ANGASTINIOTIS AND ANDROULLA ELEFTHERIOUThe Seventh Section: Stem Cell Transplantation

Allogeneic Stem Cell Transplantation in Patients with β-thalassemia: King Faisal Specialist Hospital and Research Centre Experience

A. Al-Jefri King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi ArabiaCorrespondence[email protected]
,
A. Ayas King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
,
A. Al Musa King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
,
M. Al Mahr King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
,
M. Al Saleh King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
,
S. Rifai King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
,
R. Sabbah King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
,
A. Al Seraihy King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
,
A. Al Ahmari King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
,
E. Khairy King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
,
I. Al Hassan King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
&
H. El Solh King Faisal Specialist Hospital and Research Centre (KFSH&RC), Riyadh, Saudi Arabia
 show all
Pages S183-S187 | Published online: 13 Dec 2009
 
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Abstract

From January 1998–July 2006, 62 stem cell transplantation (SCT) were performed on 60 patients with β-thalassemia from HLA-related match donors. The overall survival (OS) and event free survival (EFS) for all patients were 94 and 77%. The outcome of allogeneic SCT in our experience is satisfactory with OS 92% and EFS 77%. Transplantation at a young age and when the disease is mild offers the best outcome. More advanced disease is associated with higher rate of rejection and severe graft versus host disease.

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