Advanced search
Publication Cover
Cancer Investigation Volume 28, 2010 - Issue 9
Submit an article Journal homepage
103
Views
31
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLECausation and Prevention

Cleft Lip and Palate in Family Members of Cancer Survivors

E. TaioliDepartment of Epidemiology, SUNY Downstate Medical Center, Brooklyn, New York, USA, Department of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA Center for Research on Healthcare, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
,
C. RaginDepartment of Epidemiology, SUNY Downstate Medical Center, Brooklyn, New York, USA, Department of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA Center for Research on Healthcare, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
,
L. RobertsonDepartment of Epidemiology, SUNY Downstate Medical Center, Brooklyn, New York, USA, Department of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA Center for Research on Healthcare, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
,
F. LinkovDepartment of Epidemiology, SUNY Downstate Medical Center, Brooklyn, New York, USA, Department of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA Center for Research on Healthcare, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
,
N.E. ThurmanDepartment of Epidemiology, SUNY Downstate Medical Center, Brooklyn, New York, USA, Department of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA Center for Research on Healthcare, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
&
A.R. VieiraDepartment of Epidemiology, SUNY Downstate Medical Center, Brooklyn, New York, USA, Department of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA Center for Research on Healthcare, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Pages 958-962 | Published online: 22 Jun 2010
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

ABSTRACT

The presence of cleft lip with or without cleft palate (CL/P) in family members of cancer patients was investigated. An epidemiological questionnaire including family history of cancer and congenital oral cleft malformations was administered to 168 cancer survivors and a population-based sample of 170 healthy subjects. In the control group, 1.2% reported a family member with CL/P; among cancer survivors the figure was 4.2% (odds ratio: 3.7; 95% confidence interval: 0.75–17.8; p = .07). Among cancer survivors with a family member with CL/P, there was an apparent excess of testicular cancer and melanoma in comparison with the cancer survivors with no family history of CL/P. These preliminary results suggest a common etiologic background for cancer and CL/P.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 1,193.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.