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Cancer Investigation Volume 32, 2014 - Issue 5
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ORIGINAL ARTICLE

Intensity Modulated Arc Therapy in Bilaterally Irradiated Head and Neck Cancer: A Comparative and Prospective Multicenter Planning Study

Stéphanie Servagi VernatCorrespondence[email protected]
,
David AliDepartment of Radiation Therapy, Georges Pompidou Hospital, Paris Descartes University, Sorbonne Paris Cité, Paris, France
,
Caroline MessinaDepartment of Radiation Oncology, Centre René Gauducheau, Saint-Herblain, France
,
Pascal PommierUMR 5824 CNRS, University of Lyon,France
,
Sophie DussartUBET, Leon Berard Center, Lyon, France
,
Marc PuyraveauClinical Methodology Center, Besançon University Hospital, Besançon, France
,
Romain ViardAQUILAB, Loos les Lille,France
,
Thomas LacornerieDepartment of Radiation Oncology Cancer Center Oscar Lambret, Lille, France
,
Albert LisbonaDepartment of Radiation Oncology, Centre René Gauducheau, Saint-Herblain, France
,
Pascal FenogliettoDepartment of Radiation Oncology, Cancer Center Val D'Aurelle, Montpellier, France
,
Jocelyne MazurierDepartment of Radiation Oncology, Clinic Pasteur, Toulouse, France
,
Robin GarciaDepartment of Radiation Oncology, Saint Catherine Institut, Avignon, France
,
Gregory HangardDepartment of Radiation Oncology, Claudius Regaud Institut, Toulouse, France
,
Sophia ZefkiliDepartment of Radiation Oncology, Curie Institut, Paris, France
,
Libor MakovickaIRMA/LCPR-AC/CE UMR 6249 CNRS, University of Franche-Comte,France
&
Philippe GiraudDepartment of Radiation Therapy, Georges Pompidou Hospital, Paris Descartes University, Sorbonne Paris Cité, Paris, France
 show all
Pages 159-167 | Received 05 Feb 2013, Accepted 23 Jan 2014, Published online: 07 Mar 2014
 
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Abstract

A dosimetric comparison was made of Helical Tomotherapy (HT) and Rapid'Arc® (RA) in 115 patients with head and neck carcinoma included in a prospective and multicentric study. HT and RA provided highly conformal plans that easily complied with dose volume constraints for organs at risk. HT reduced high doses to the planning target volumes (PTVs) compared to RA and provided a more homogeneous dose distribution but with an increased Non Tumoral Integral Dose (NTID) than RA. However, the clinical consequences of these dosimetric advantages and disadvantages need further investigation.

Notice of Correction

Changes have been made to this article since its original online publication date of 7 March 2014.

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