Fluorescent labels in biosensors for pathogen detection

Abstract

Infectious diseases caused by pathogens have become a life-threatening problem for millions of people around the world in recent years. Therefore, the need of efficient, fast, low-cost and user-friendly biosensing systems to monitor pathogen has increased enormously in the last few years. This paper presents an overview of different fluorescent labels and the utilization of fluorescence-based biosensor techniques for rapid, direct, sensitive and real-time identification of bacteria. In these biosensors, organic dyes, nanomaterials and rare-earth elements are playing an increasing role in the design of biosensing systems with an interest for applications in bacterial analysis.

• Carbon nanotube
• carbon quantum dot
• fluorescence-based biosensor
• fluorescent labels
• organic dye
• pathogen detection
• rare-earth elements
• semiconductor quantum dots

Declaration of interest

The authors report no declarations of interest. The authors are grateful to the financial support from National Science Foundation of China: Investigation of Fast Pathogen Detection Based on Novel Macroporous Chips Technology (21275105), National Recruitment Program of Global Experts (NRPGE), the Hundred Talents Program of Sichuan Province (HTPSP), and the Startup Funding of Sichuan University for setting up the Research Center of Analytical Instrumentation.