Radiation Treatment for Age-Related Macular Degeneration

Abstract

Age-related macular degeneration (AMD) remains a devastating cause of visual loss among elderly individuals. While considerable progress has been made towards combating the disease, most recently with intravitreal anti-VEGF agents, visual outcomes are still limited by continued retinal pigment epithelium (RPE) degeneration and subsequent neurosensory retinal atrophy. Among the promising new treatment options being explored, radiotherapy appears apt to address the multifactorial etiology of AMD. Current investigative studies underway will hopefully yield clinical efficacy to complement this theoretical suitability for arresting visual loss.

Keywords::

• Radiation
• Age-Related Macular Degeneration
• Retina
• Choroidal Neovascular Membrane
• Brachytherapy

ACKNOWLEDGMENT

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Disclosures: RPS, PKK, and DMM serve as consultants to Oraya Therapeutics, Inc., Newark, California.