Emerging Therapies for the Treatment of Neovascular Age Related Macular Degeneration

Abstract

Numerous drugs that show promise in the treatment of neovascular age related macular degeneration are currently being evaluated in early clinical trials. Some of these drugs target the vascular endothelial growth factor pathway while others act on different targets along the angiogenesis cascade. The mechanism of action of these novel therapeutics and the results of early clinical trials will be discussed along with a review of angiogenesis.

Keywords::

• macular degeneration
• vascular endothelial growth factor
• angiogenesis

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.