Imaging Characteristics of Dry Age-Related Macular Degeneration

Abstract

Purpose: To review the current literature regarding the imaging characteristics of dry age-related macular degeneration (AMD) lesions, with a special focus on drusen and geographic atrophy imaging. We also explore the role of novel approach of hyperspectral imaging in AMD.

Methods: Review of current literature as well as findings in a small group of patients imaged with hyperspectral imaging.

Results: The use of optical coherence tomography, and especially fourier-domain devices, has enhanced our ability to classify various lesions of dry AMD. The increasing role of autofluorescence in characterization and prognostication in geographic atrophy is reviewed. The advances made in automated detection and multimodal imaging are highlighted, with their potential to revolutionize this area of research.

Conclusions: Recent advances in retinal imaging have improved our understanding of the characteristics and prognostication of dry AMD, with an increasing role for multimodal imaging and image correlations. The potential future role of hyperspectral imaging in dry AMD is also presented herein.

Keywords::

• hyperspectral
• imaging
• dry age-related macular degeneration
• OCT
• autofluorescence

ACKNOWLEDGMENT

The authors would like to acknowlege NEI grant support in this work.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.