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Abstract
Tears of the retinal pigment epithelium (RPE) are a known and potentially catastrophic complication of exudative age-related macular degeneration (AMD). Eyes with vascularized retinal pigment epithelial detachments (PED) are especially at risk for the development of RPE tears. This long-recognized complication faces increased scrutiny in an era of improved anti-angiogenic treatments for AMD, particularly given that these newly developed therapeutics have been implicated as a potential factor in the formation of some RPE tears.
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper. Publication of this article was supported by funding received from Research to Prevent Blindness, New York, New York, USA. Andrew J Barkmeier receives grant support from Regeneron - VIEW 1 trial, NEI - CATT trial, and NEI - AREDS 2 trial.