Cancer-associated Retinopathy with Retinal Periphlebitis in a Patient with Ovarian Cancer

Abstract

Purpose: To describe a case of cancer-associated retinopathy (CAR) due to ovarian cancer presenting with retinal periphlebitis and a negative-type pattern electroretinogram (ERG).

Design: Case report.

Methods: Retrospective chart review.

Results: A negative-type ERG in the setting of progressive vision loss and retinal periphlebitis led to the discovery of metastatic ovarian cancer and ultimately the diagnosis of CAR.

Conclusions: CAR can present with periphlebitis and a negative-type ERG. Greater awareness of these associations may allow for earlier detection of future cases.

KEYWORDS::

• cancer-associated retinopathy
• ovarian cancer
• paraneoplastic syndrome
• periphlebitis
• vasculitis

ACKNOWLEDGMENTS

Dr. Stephen Kim had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Supported by Research to Prevent Blindness (CEK) and National Eye Institute core grant 1 P30 EY12576-05 (CEK).

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.