Optic Disc Neovascularization Revealing Neurosyphilis

Abstract

Purpose: To report a case of neurosyphilis revealed by bilateral optic disc neovascularization.

Design: Case report. Methods: A 39-year-old man presented with a 6-month history of progressive visual loss (20/25 RE, 20/1200 LE) and transient headaches. Fundus examination demonstrateda 1+ vitritis, mild macular edema and large optic disc neovascularization in both eyes. Serological tests for syphilis were positive. Results: Specific antibiotics and systemic steroids were undertaken and complete regression of disc neovascularization was observed within 6 months.

Conclusion: Optic disc neovascularization, which is a rare manifestation of chronic uveitis, may lead to the diagnosis of neurosyphilis and be successfully treated by specific antibiotic and steroid therapy.

KEYWORDS::

• Chronic uveitis
• Neurosyphilis
• Optic disc neovascularization

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.