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Research Article

Cat-Scratch Disease

, MD, MSc & , MD, PhD
Pages 148-154 | Received 22 May 2013, Accepted 07 Aug 2013, Published online: 09 Oct 2013
 

Abstract

Purpose: To discuss the systemic and ocular manifestations, diagnosis and treatment of Bartonella infection.

Method: Review of the literature.

Results: Bartonella are facultative intracellular Gram-negative rods that infect the erythrocytes or endothelial cells and are related to cat scratch disease (CSD). Bartonella henselae infection has localized or systemic features; the ocular diseases related to Bartonella affect 5--10% of patients with CSD. The diagnosis is based on clinical findings and laboratory tests. The indication of antibiotic therapy depends on the manifestation of the Bartonella infection, the host immunity and the patient's age.

Conclusion: Physicians should look for Bartonella henselae in cases of follicular conjuntivitis and regional limphadenopathy, neuroretinitis or retinal infiltrates; currently, serological tests can confirm the clinical suspicion of this infection.

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