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Research Article

Vogt-Koyanagi-Harada Disease: Clinical and Demographic Characteristics of Patients in a Specialized Eye Hospital in Turkey

, MD, , MD, , MD, , MD & , MD
Pages 277-286 | Received 19 Aug 2013, Accepted 14 Oct 2013, Published online: 11 Dec 2013
 

Abstract

Purpose: To evaluate clinical and demographic features of Vogt-Kayanagi-Harada disease (VKH) disease in Turkish patients and compare them with previously published data.

Methods: Demographic and clinical features of 32 patients diagnosed as VKH in a tertiary referral center were retrospectively reviewed.

Results: The mean age at presentation was 33.6 ± 10.4 years. Seventy-five percent of the patients were female and 62.5% of the patients presented during the last 2 years. The disease was complete in 31.2%, incomplete in 50%, and probable in 18.8% of the patients. The clinical course was acute in 50%, chronic recurrent in 34.4%, and chronic in 15.6%. The most common findings were bilateral serous retinal detachment ± papillitis in acute cases and retinal pigment epithelial changes of the macula in chronic cases.

Conclusions: Although rare in Turkey, VKH disease seems to have increased during the last few years. The disease is incomplete and acute in half of the patients and has a quite good visual prognosis.

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