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Gynecological Endocrinology Volume 30, 2014 - Issue 5
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Adolescent PCO

Metformin, oral contraceptives or both to manage oligo-amenorrhea in adolescents with polycystic ovary syndrome? A clinical review

Stefano PalombaDepartment of Obstetrics and Gynecology, Arcispedale S. Maria Nuova of Reggio Emilia, IRCCS Reggio EmiliaItalyCorrespondence[email protected]
,
Caterina MaterazzoDepartment of Obstetrics and Gynecology, Arcispedale S. Maria Nuova of Reggio Emilia, IRCCS Reggio EmiliaItaly;Department of Obstetrics and Gynecology, University Magna Graecia of Catanzaro CatanzaroItaly
,
Angela FalboDepartment of Obstetrics and Gynecology, Arcispedale S. Maria Nuova of Reggio Emilia, IRCCS Reggio EmiliaItaly
,
Francesco OrioDepartment of Endocrinology, Parthenope University of Naples NaplesItaly
,
Giovanni Battista La SalaDepartment of Obstetrics and Gynecology, Arcispedale S. Maria Nuova of Reggio Emilia, IRCCS Reggio EmiliaItaly;University of Modena and Reggio Emilia ModenaItaly
&
Charles SultanUnité d'Endocrinologie Gynécologie Pédiatriques, Hôpital Arnaud de Villeneuve CHU MontpellierFrance
Pages 335-340 | Received 01 Dec 2013, Accepted 12 Dec 2013, Published online: 09 Jan 2014
 
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Abstract

The management of oligo-amenorrhea in adolescent patients with polycystic ovary syndrome (PCOS) represents an important and difficult challenge. Metformin and/or oral contraceptives (OCs) are different strategies widely proposed in these patients. The objective of the current review was to provide an overview on the use of metformin and/or OCs for the management of oligo-amenorrhea in adolescents with PCOS underlining their potential risks and benefits in order to help the clinician to choose the best patients’ tailored treatment.

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