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Platelets Volume 22, 2011 - Issue 1
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Spotlight Article

P2Y12 receptor in platelet activation

Soochong Kim Department of Physiology,; Sol Sherry Thrombosis Research Center,
&
Satya P. Kunapuli Department of Physiology,; Sol Sherry Thrombosis Research Center,; Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA, USACorrespondence[email protected]
, PhD
Pages 54-58 | Received 15 Apr 2010, Accepted 26 May 2010, Published online: 13 Jan 2011
 
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Abstract

ADP plays an important role in hemostasis and thrombosis. The P2Y12 receptor, activated by ADP, plays a central role in platelet activation and thrombus formation. Thus, the P2Y12 receptor has been an effective target for antithrombotic drugs.

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