Good results can be obtained with CO2 laser treatment of divided nevi with a relatively small size and nodular character (like intradermal nevi). Better results are also obtained when lesions are located in the flabby periorbital skin, where the risk of scar formation is lower. Lesions in tense anatomical positions, such as the regio zygomatica, are more likely to result in complications. We regard involvement in the inside of the tarsal plates or the nasolacrimal canal as a contraindication to CO2 laser treatment.
The treatment strategy for divided eyelid nevi should be individualized and based on the size, lesion characteristics, and site. The CO2 laser ablation can simplify the treatment procedure and achieve good treatment results in selected lesions.