Advanced search
Publication Cover
Clinical and Experimental Hypertension Volume 34, 2012 - Issue 8
Submit an article Journal homepage
56
Views
3
CrossRef citations to date
0
Altmetric
Research Article

Relationship Between Renal Hemodynamics and Urinary Type IV Collagen in Patients with Essential Hypertension

Daijiro EnomotoDepartment of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon City, Japan
,
Takafumi OkuraDepartment of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon City, JapanCorrespondence[email protected]
,
Tomoaki NagaoDepartment of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon City, Japan
,
Masanori JotokuDepartment of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon City, Japan
,
Jun IritaDepartment of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon City, Japan
,
Ken-ichi MiyoshiDepartment of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon City, Japan
&
Jitsuo HigakiDepartment of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon City, Japan
 show all
Pages 612-616 | Received 07 Feb 2012, Accepted 30 Mar 2012, Published online: 07 May 2012
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Urinary type IV collagen excretion (uT4C) in diabetic patients is higher than in normal subjects. In this study, we investigated the relationship between uT4C and renal hemodynamics in 42 patients with essential hypertension. The renal resistive index (RI) is calculated from blood flow velocities measured using pulsed-wave in interlobar arteries. There was a significant correlation between uT4C to creatinine ratio (uT4C/uCr) and age, hemoglobin A1c (HbA1c), and RI. A stepwise regression analysis showed that RI was independently associated with uT4C/uCr. These results indicated that uT4C may be a marker of renovascular stiffness due to glomerulosclerosis in patients with essential hypertension.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later
PDF download + Online access
  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart
* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.