Marisa J. S. Frederico, Simoni l. Justo, Gabrielle da Luz, Sabrina da Silva, Cleber Medeiros, Viviane A. Barbosa, Luciano A. Silva, Carina R. Boeck, Ricardo A. De Pinho, & Cl udio T. De Souza. Exercise training provides cardioprotection via a reduction in reactive oxygen species in rats submitted to myocardial infarction induced by isoproterenol. Free Radical Research, October 2009;43(10):957–964.
The authors would like to correct an error that occurred in this publication.
Additions have been made to the Statistical analysis paragraph on page 959, the Results section on page 959 and on page 960.
Table II. Comparison of survival rates.
The corrected paragraphs and are given below. Please note these changes do not alter either data values or the conclusion of the study.
Statistical analysis
Biochemical data were expressed as means and mean standard errors, and analysed statistically by one-way variance analysis (ANOVA), followed by the Tukey posthoc test. The results of blot analysis were expressed as the means ± SEM of densitometric units. Differences between the groups were evaluated using one-way analysis of variance (ANOVA). When ANOVA indicated significance, a Tukey post hoc test was performed. Survival rates were compared using chi-square test, because we had a single time point observation, and the level of significance was set at p < 0.05. The software used for analysis of the data was the Statistical Package for the Social Sciences (SPSS) version 12.0 for Windows.
Results
Exercise reduces mortality and levels of CK-MB induced by isoproterenol
The administration of isoproterenol produces high rates of mortality [31]. Interestingly, in the present study, the sample was sufficient to prove with 95% confidence that exercise training (ET + ISO) increased the rate of survival of animals that received isoproterenol (80%), when compared to the C + ISO (40%) group (c2 = 15.0; df = 3.0, p = 0.002 by chi-square test), demonstrating the beneficial effect of previous exercise training in this model ().
This paper was first published online on Early Online on 4 April 2012.