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ORIGINAL ARTICLE

Monitoring Population Levels of Alcohol Consumption in Pregnant Women: A Case for Using Biomarkers

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Pages 569-573 | Published online: 10 Jun 2013
 

Abstract

A challenge to biochemically monitoring alcohol consumption in pregnancy is the prohibitive costs of collecting thousands of blood samples. This pilot study looks at the feasibility of using residual samples to monitor chronic and acute alcohol consumption in pregnancy. Residual anomalies screening samples (n = 150, 2006/7) were tested for carbohydrate-deficient transferrin (CDT, chronic marker) and ethyl glucuronide (EtG, acute marker). Valid readings were obtained for CDT but not EtG. These results pave the way for a larger representative study, to provide, for the first time, a national biochemical baseline estimate of chronic alcohol consumption in the pregnant population.

RÉSUMÉ

Un défi à la surveillance biochimique de la consommation d'alcool pendant la grossesse est le coût prohibitif de la collecte des milliers d’échantillons sanguins. Cette étude porte sur la faisabilité d'utiliser des échantillons résiduels de surveiller la consommation d'alcool, chronique et aiguë, pendant la grossesse. Échantillons de dépistage des anomalies résidual été testés pour les carbohydrate deficient transferrin (CDT) and ethyl glucuronide (EtG). Lectures valides ont été obtenues pour TDC mais pas GEt. Ces résultats ouvrent la voie à une étude représentative, de fournir, pour la première fois, une estimation nationale ligne de base biochimique la consommation chronique d'alcool en la population de femmes enceintes.

RESUMEN

Un reto para la observación bioquímica del consumo de alcohol durante el embarazo es el costo prohibitivo de recoger miles de muestras de sangre. Este estudio analiza la viabilidad de la utilización de muestras residuales para observar el consumo de alcohol crónico y agudo en el embarazo. La selección de muestras residuales de anomalías (n = 150, 2006/7) fueron probadas para carbohydrate deficient transferrin (CDT) y ethyl glucuronide (EtG). Se obtuvieron lecturas válidas para CDT pero no EtG. Estos resultados allanan el camino para un estudio representativo, para proporcionar por primera vez, una estimación nacional de base bioquímica del consumo crónico de alcohol en la población embarazada.

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