The frequency of serum amyloid A2 alleles in the Japanese population

Abstract

The incidence of serum amyloid A2 alleles (SAA_2α and SAA_2β) in the Japanese population was analyzed by PCR-RFLP analysis. The SAA_2α allele was predominant (approximately 90%) in both healthy controls and adult patients with rheumatoid arthritis. There was no significant association of allele patterns with AA amyloidosis in the patient group. These results are discussed in comparison with those of previous reports from other areas.

Key Words:

• serum amyloid A. alleles
• freyuency
• amyloidosis
• rheumatoid arthritis
• Japanese