Serum omentin-1 levels are inversely associated with the presence and severity of coronary artery disease in patients with metabolic syndrome

Abstract

Context: Omentin-1, an adipokine secreted from visceral adipose tissue, has been reported to be associated with coronary artery disease (CAD) and metabolic disorders.

Objective: To clarify the relationship between serum omentin-1 levels and the presence and severity of CAD in patients with metabolic syndrome (MetS).

Methods: We measured serum omentin-1 levels in 175 consecutive patients with MetS and in 46 controls.

Results: Serum omentin-1 levels are inversely associated with the presence and angiographic severity of CAD in MetS patients.

Conclusions: Serum omentin-1 might be a potential biomarker to predict the development and progression of CAD in MetS patients.

Keywords::

• Adipokines
• biomarker
• cardiometabolic syndrome
• coronary atherosclerosis index

Acknowledgements

We thank the catheterization laboratory staff for their supports to this study.

Declaration of interest

The authors report no conflicts of interest.