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Modern Rheumatology Volume 26, 2016 - Issue 2
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CASE REPORT

A case of angioimmunoblastic T-cell lymphoma with high serum VEGF preceded by RS3PE syndrome

Tetsuya TabeyaDepartment of Gastroenterology, Rheumatology and Clinical Immunology Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan;Department of Internal Medicine, Dohkohkai Hospital, Sapporo, Hokkaido, JapanCorrespondence[email protected]
,
Toshiaki SugayaDepartment of Gastroenterology, Rheumatology and Clinical Immunology Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
,
Chisako SuzukiDepartment of Gastroenterology, Rheumatology and Clinical Immunology Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
,
Motohisa YamamotoDepartment of Gastroenterology, Rheumatology and Clinical Immunology Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
,
Takayuki KanasekiDepartment of Pathology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
,
Hiroko NoguchiDepartment of Pathology, Teine Keijinkai Hospital, Sapporo, Hokkaido, Japan
,
Yasuyoshi NaishiroDepartment of Gastroenterology, Rheumatology and Clinical Immunology Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
,
Tadao IshidaDepartment of Gastroenterology, Rheumatology and Clinical Immunology Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
,
Hiroki TakahashiDepartment of Gastroenterology, Rheumatology and Clinical Immunology Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
&
Yasuhisa ShinomuraDepartment of Gastroenterology, Rheumatology and Clinical Immunology Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
 show all
Pages 281-285 | Received 12 Jun 2013, Accepted 15 Oct 2013, Published online: 02 Dec 2013
 
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Abstract

We report the case of a 76-year-old man diagnosed with angioimmunoblastic T-cell lymphoma (AITL) with high serum vascular endothelial growth factor (VEGF) preceded by Remitting seronegative symmetrical synovitis with pitting edema syndrome. He suffered respiratory discomfort caused by large amounts of pleural effusion. Interestingly, changes in serum VEGF measured over time were similar to changes in pleural effusion. Whether VEGF is related to the pathological condition of AITL is a very important question.

Conflict of interest

None.

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