Infertility treatment for azoospermic patients with a history of infectious parotitis (mumps) using combined techniques

Abstract

Purpose: The purpose of this study was to investigate the clinical efficacy of in vitro maturation-intracytoplasmic sperm injection (IVM-ICSI) technique on the treatment of azoospermic patients with a history of infectious parotitis (mumps). Methods: Spermatozoa were obtained from the testes of azoospermic patients with a history of mumps and fertilized by ICSI. Eggs were retrieved from the spouse of patients in the natural cycle. Fertilized embryos were transferred into the uterus of patients’ respective spouses. Results: Live sperm were retrieved from 16 of out of 24 (67%) azoospermic patients with a history of mumps. Using IVM-ICSI, the normal fertilization rate was 71.2%. A total of 23 treatment cycles were completed in the spouses of 16 patients and of these, 9 patients’ spouses became pregnant (a pregnancy rate of 39.1%). The success rate for infertility treatment of mumps patients was equally high at 56.3% (9/16). Conclusion: The IVM-ICSI technique is a simple, effective and economic method for infertility treatment in azoospermic patients with a history of mumps

Keywords::

• natural cycle
• IVM
• ICSI
• mumps
• azoospermia

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.