Significant alleviation of Darier's disease with fractional CO2 laser

Abstract

Darier's disease (DD) is a dominantly inherited genodermatosis with highly variable expression. It is characterized by symmetrical hyperkeratotic papules affecting seborrheic areas and extremities. The existence of unsightly lesions could lead to discomfort and social handicap. Conventional treatment consists of topical and systemic steroids and/or retinoids alleviating DD. Ablative lasers also have been used to treat these conditions with variable results and side effects. To the best of our knowledge, fractional CO2 laser has never been used to treat DD. We present a case of a 36-year-old woman with verrucous and hyperkeratotic plaques of the forehead significantly improved after two sessions of fractional CO2 laser treatment. Neither scars nor pigmentary disorders were noted.

Key Words::

• Darier's disease
• Darier–White's disease
• fractional CO2 laser
• keratosis follicularis

Declaration of interest: The authors report no declarations of interest. The authors alone are responsible for the content and writing of the paper.

Notice of Correction

Changes have been made to this article since its original online publication date of 17 December 2014.