![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
Whole-body autoradiography (WBA) is a technique that has been available for many years for studying the biological fate of chemicals. This technique, which is most frequently employed with radiolabeled chemicals, provides a visual analysis of tissue distribution. In recent years, there has been an increasing interest in using this technique in studies of the absorption, distribution, metabolism, and elimination (ADME) of chemicals. An important factor in the increasing use of WBA is the ability to utilize image analysis technology to quantitate WBA data. In this article, the status of quantitative WBA is discussed. In addition, this article discusses recent developments in the application of WBA in the field of toxicology.