Prenatal Diagnosis and Pregnancy Outcome Analysis of Polyhydramnios

ABSTRACT

The aim of the study was to investigate the etiology and pregnancy outcomes in mothers with polyhydramnios through prenatal diagnosis and pregnancy outcome analysis of pregnant women with polyhydramnios. One hundred and thirty women were enrolled. Fifty pregnant women with polyhydramnios were categorized as the case group, and 80 pregnant women with normal amniotic fluid were categorized as the control group. The causes of polyhydramnios and the pregnancy outcomes were analyzed. Two cases had chromosomal abnormalities, seven had severe α-thalassemia, 15 had fetal anomalies, four had maternal-fetal diseases and 22 had unexplained idiopathic polyhydramnios. Significantly, higher occurrences of cesarean section, preterm birth, fetal anomaly, fetal distress, fetal macrosomia and female fetuses occurred in patients with polyhydramnios than in patients without polyhydramnios. Polyhydramnios is associated with a higher occurrence of adverse perinatal outcomes. Intensive monitoring of the maternal-fetal condition and prenatal diagnosis is important in patients with polyhydramnios.

Keywords:

• polyhydramnios
• prenatal diagnosis
• pregnancy outcome

Acknowledgements

We are grateful to all family members who contributed to the study.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article. This study was supported by the Guangxi Natural Science Foundation (2014GXNSFAA118246) and by the grant from the Guangxi Health Department (Z2014042). The funding sources had no role in the study design, data collection and analysis, the decision to publish or the preparation of the manuscript.