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Clinical Toxicology Volume 49, 2011 - Issue 6
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Contact dermatitis caused by dimethylfumarate in Argentina

A. Lo BalboCentro de Investigaciones Toxicológicas, Juan B. Alberdi 2986, Ciudad de Buenos Aires, ArgentinaCorrespondence[email protected]
,
M. J. GotelliCentro de Investigaciones Toxicológicas, Juan B. Alberdi 2986, Ciudad de Buenos Aires, Argentina
,
W. P. Mac CormackInstituto Antártico Argentino, Cerrito 1248, Ciudad de Buenos Aires, Argentina;Cátedra de Biotecnología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina
,
N. KoganCentro de Investigaciones Toxicológicas, Juan B. Alberdi 2986, Ciudad de Buenos Aires, Argentina
&
C. GotelliCentro de Investigaciones Toxicológicas, Juan B. Alberdi 2986, Ciudad de Buenos Aires, Argentina
Pages 508-509 | Received 30 Mar 2011, Accepted 01 Jun 2011, Published online: 15 Jul 2011
 
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Abstract

For the first time in Argentina, we describe an outbreak of contact dermatitis. New pairs of shoes caused intense pruritus, pain, and eruption, followed by edema, blisters, and a severe negative impact on the epidermal barrier of the feet. We identify dimethylfumarate as the causal agent and suggest an analytical method for its fast identification.

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