Primary systemic amyloidosis

Early diagnosis and therapy can improve survival rates and quality of life

Archana Roy Dr Archana Roy is assistant professor, division of hospital medicine, and Dr Vivek Roy is assistant professor, department of internal medicine, division of hematology and oncology, Mayo Clinic Jacksonville, Jacksonville, Florida.Correspondence[email protected]

, MD &

Vivek Roy Dr Archana Roy is assistant professor, division of hospital medicine, and Dr Vivek Roy is assistant professor, department of internal medicine, division of hematology and oncology, Mayo Clinic Jacksonville, Jacksonville, Florida.

, MD

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Primary systemic amyloidosis is a light-chain immunoglobulin disorder that causes nonlocalized or multisystem symptoms. Patients with cardiac involvement have a poor prognosis. Fortunately, many effective treatments have become available in recent years. Early diagnosis and institution of treatment is critical to improving survival rates and quality of life. In this article, the authors highlight common clinical presentations, suggest diagnostic workup techniques, and discuss treatment options, including autologous stem cell transplantation.

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Primary systemic amyloidosis

Early diagnosis and therapy can improve survival rates and quality of life

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Primary systemic amyloidosis

Early diagnosis and therapy can improve survival rates and quality of life

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