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Abstract
The objective of this research was to assess the alcohol effect on E-rosette formation in vitro. The results reveal that the intoxicating dose of alcohol (0.2?-5.0?) in healthy volunteers and alcoholics' blood can differently affect the E-rosette formation: in the healthy volunteers it suppressed while in the alcoholics it stimulated the E-rosette formation. Both the suppression and stimulation were closely dependent on the alcohol consumption. Though the blood of alcoholics contained fewer E-rosette forming cells than that of the healthy volunteers, the infusion of 2.0? alcohol in vitro to the alcoholics' blood raised their E-rosette formation to the level of healthy volunteers.