Publication Cover
Amyloid
The Journal of Protein Folding Disorders
Volume 16, 2009 - Issue 3
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Letter to the Editor

Rituximab therapy in nephrotic syndrome due to AH amyloidosis

, , , , &
Pages 178-180 | Published online: 19 Sep 2009
 

Abstract

We report a patient with AH amyloidosis associated with lymphoplasmacytic leukemia that has remained in a stable state with a nephrotic syndrome for 17 months since the commencement of cyclic rituximab therapy aimed at suppression of pathogenetic γ heavy chains. Free light chains in serum and CD20-positive cells in peripheral blood were useful as hematological markers in the patient. Rituximab might be a potent therapeutic option for AH amyloidosis associated with a B-cell lymphoproliferative disorder.

Abbreviations
AH=

AH amyloidosis

AL=

AL amyloidosis

CD=

cluster differentiation

FLCs=

free light chains

WBC=

white blood cell

Abbreviations
AH=

AH amyloidosis

AL=

AL amyloidosis

CD=

cluster differentiation

FLCs=

free light chains

WBC=

white blood cell

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