Abstract
Summary
A total of 52 of 238 patients (22%) with non-Hodgkin's lymphoma presented with disease in a primary extranodal site. The gastrointestinal-tract was the commonest site involved (50%) and diffuse large cell was the commonest histological sub-type of the lymphoma (64%). Survivorship analysis of these patients, treated predominantly with chemotherapy, suggests that long-term survival is associated with: (1) low-grade malignancy—median survival > 120 months; (2) localized disease or spread of disease confined to the regional lymph nodes—median survival 65.5 months; and (3) the use of aggressive combination chemotherapy for intermediate grade malignancy when the disease is localized or spread is confined to the regional lymph nodes—median survival > 110 months.
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