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Original Article

Lymphatic Transport of Cholesterol in the Human Being. Effect of Dietary Cholesterol

, &
Pages 227-235 | Received 25 Mar 1970, Accepted 02 Jun 1970, Published online: 08 Jul 2009
 

Abstract

The effect of dietary cholesterol on lymphatic cholesterol transport was studied in 6 subjects cannulated in their left thoracic duct. Feeding a fatty meal increased cholesterol transport 2–3-fold over the fasting state. Addition of cholesterol to the fat fed led to no significant further increase in lymphatic cholesterol transport. The results indicate that in the intestinal tract dietary cholesterol is mixed with a relatively much larger pool of endogenous sterol that already almost saturates the absorption capacity of the intestine for cholesterol.

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