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Xenobiotica
the fate of foreign compounds in biological systems
Volume 10, 1980 - Issue 12
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Research Article

Metabolism of limonene-1,2-epoxide in the rat

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Pages 859-861 | Received 17 Apr 1980, Published online: 22 Sep 2008
 

Abstract

1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates.

2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, β-mentha-2,8-dien-1-α and -β-ol and β-mentha-1,8-dien-6-α and -β-ol were not observed.

3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.

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