Abstract
1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates.
2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, β-mentha-2,8-dien-1-α and -β-ol and β-mentha-1,8-dien-6-α and -β-ol were not observed.
3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.