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Ultrastructural Pathology Volume 22, 1998 - Issue 1
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Low-Grade Spindle Cell Carcinoma of the Kidney

Josep Lloreta Department of Pathology, Hospital del Mar IMAS-IMIM, Autonomous University of Barcelona, Barcelona, Spain
,
Josep Maria Corominas Department of Pathology, Hospital del Mar IMAS-IMIM, Autonomous University of Barcelona, Barcelona, Spain
,
Assumpció Munné Department of Pathology, Hospital del Mar IMAS-IMIM, Autonomous University of Barcelona, Barcelona, Spain
,
David Dominguez Department of Pathology, Hospital del Mar IMAS-IMIM, Autonomous University of Barcelona, Barcelona, Spain
,
Oscar Bielsa Department of Urology, Hospital del Mar-IMAS-IMIM, Autonomous University of Barcelona, Barcelona, Spain
,
Antoni Gelabert Department of Urology, Hospital del Mar-IMAS-IMIM, Autonomous University of Barcelona, Barcelona, Spain
&
Sergi Serrano Department of Pathology, Hospital del Mar IMAS-IMIM, Autonomous University of Barcelona, Barcelona, Spain
 show all
Pages 83-90 | Received 23 May 1997, Accepted 15 Jul 1997, Published online: 10 Jul 2009
 
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Abstract

The authors report a renal cell carcinoma composed largely of spindle cells of Fuhrman's nuclear grade II in which the bland appearance of the cells and low mitotic index were reminiscent of a benign or low-grade smooth muscle tumor. Keratin immunostaining was positive, but evidence of epithelial differentiation was obtained by electron microscopy. The tumor was an incidental finding and it did not invade the perirenal fat or the renal vein. Follow-up is only 24 months but the histological features suggest that the prognosis may be better than that of a classic sarcomatoid renal cell carcinoma.

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