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Hemoglobin
international journal for hemoglobin research
Volume 15, 1991 - Issue 6
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Original Article

Detection of the HB Quong SZE Mutation in a Chinese Family by Selective Amplification of the α2-Globin Gene and Restriction Map Analysis with MSP I

S. Liang Guangxi Medical College Nanning, Guangxi, PR, China
,
X-J. Wen Guangxi Medical College Nanning, Guangxi, PR, China
&
W-X. Lin Guangxi Medical College Nanning, Guangxi, PR, China
Pages 535-540 | Received 01 Mar 1991, Accepted 31 Jul 1991, Published online: 07 Jul 2009
 
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Abstract

The polymerase chain reaction technique combined with restriction map analysis with Msp I and hybridization with synthetic oligonucleotide probes has been used to identify Hb Quong Sze [α25(H8)Leu→Pro] in a Chinese family in Guangxi (Quong Sze), P.R. China. Our data and those described in an earlier publication (1) indicate that the Hb Quong Sze carriers originate from the same province of the People's Republic of China, namely Guangxi.

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