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Scandinavian Journal of Urology and Nephrology Volume 34, 2000 - Issue 205
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Research Article

Carcinoma in situ in the Testis

Mikael Rørth Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
,
Ewa Rajpert-De Meyts Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
,
Lennart Andersson Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
,
Klaus-Peter Dieckmann Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
,
Sophie D. Fosså Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
,
Kenneth M. Grigor Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
,
William F. Hendry Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
,
Harry W. Herr Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
,
Leendert H.J. Looijenga Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
,
J. Wolter Oosterhuis Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
&
Niels E. Skakkebaek Department of Oncology, University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark
 show all
Pages 166-186 | Published online: 09 Jul 2009
 
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Abstract

Carcinoma in situ (CIS) of the testis is a common precursor of germ-cell tumours in adults and adolescents, with the exception of spermatocytic seminoma. This article reviews existing knowledge on the pathobiology, genetic aspects and epidemiology of CIS, discusses current hypotheses concerning pathogenesis and invasive progression of germ-cell neoplasms and provides guidelines for diagnosis and clinical management of CIS.

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