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Abstract
A patient series of 37 with a total of 47 radiation-induced cancers is reviewed. In the entire material of radiation burns, which is presented in another connexion, the cancer incidence was 20 per cent. Squamous cell carcinoma was the most frequent type, basal cell carcinoma also fairly frequent, and sarcoma distinctly rarest. Etiologically the benign diseases of the skin and subcutaneous tissues by far made up the largest group of indications for irradiation. The time of latency from irradiation to tumour averaged 23 to 30 years.
Seven of a total of 30 radiation cancer patients treated by plastic surgery died of radiation cancer and one of complications of a radiation burn. An inoperable recurrence, in general, appeared immediately, and even the deaths latest within two years from termination of treatment. Recurrency was local in 6 instances and only in one attributable to primary metastases. In regard to the patients making recovery, of whom three had also regional lymph node metastases, the average period of follow-up was 4.3 years. The importance of an early preventive treatment is emphasized.