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Research Article

Complement defects in aged mice compromise phagocytosis of Pseudomonas aeruginosa

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Pages 26-32 | Published online: 02 Jul 2009

References

  • Liesgang TJ. Bacterial and fungal keratitis. In: Kaufman HE, Barron BA, McDonald MD, Waltman SR. The Cor-nea, New York, NY: Churchill Livingstone;1988:217–270.
  • Hazlett LD, Rosen DD, Berk RS. Age-related suscepti-bility to Pseudomonas aeruginosa ocular infections in mice. Infect Immun. 1978;20:25–29.
  • Berk RS, Iglewski BH, Hazlett LD. Age-related suscep-tibility of mice to ocular challenge with Pseudomonas exotoxin A. Infect Immun. 1981;33:90–94.
  • Hazlett LD, Berk RS. The murine ocular response to P. aeruginosa: immunological studies. In: Chandler, J. Pro-ceedings International Symposium on Immunology and Immunopathology of the Eye, New York, NY: Masson Publishing Inc; 1984:179–182.
  • Kwon B, Hazlett LD. Association of CD4+ T cell-de-pendent keratitis with genetic susceptibility to Pseudomo-nas aeruginosa ocular infection. J Immunol. 1998;159: 6283–6290.
  • Cleveland RP, Hazlett LD, Berk RS, Leon MA. The role of complement in Pseudomonas ocular infections. Invest Ophthalmol Vis Sci. 1983; 24:237–242.
  • Hazlett LD, Berk RS. Effect of C3 depletion on experi-mental Pseudomonas aeruginosa ocular infection:histo-pathological analysis. Infect Immun. 1984;43:783–790.
  • Hazlett LD, Rosen DD, Berk RS. Experimental Pseudo-monas endophthalmitis in immunosuppressed inbred mice. Ophthalmic Res. 1977; 9:374–380.
  • Hazlett LD, Rosen D, Berk RS. Experimental Pseudomo-nas eye infection in cyclophosphamide treated mice. Invest Ophthalmol. 1977;16:649–652.
  • Pier GB. Pseudomonas aeruginosa: a key problem in cystic fibrosis. ASM News. 1998;64:339–347.
  • Hobden JA, Masinick, SA, Barrett RP, Hazlett LD. Aged mice fail to upregulate ICAM-1 after Pseudomonas aeruginosa corneal infection. Invest Ophthalmol Vis Sci. 1995;36: 1107–1114.
  • Hobden JA, Masinick SA, Barrett RP, Hazlett LD. Proinflammatory cytokine deficiency and pathogenesis of Pseudomonas aeruginosa keratitis in aged mice. In-fect Immun. 1997;65:2754–2758.
  • Figdor GC, van Kook Y. Regulation of cell adhesion. In: Harlan JM, Liu DY. Adhesion, Its Role in Inflam-matory Disease, New York, NY: W.H. Freeman and Co;1992:151–182.
  • Hazlett LD, Burns-Kreindler F, Berk RS, Barrett RP. Aging alters the phagocytic capability of inflammatory cells induced into cornea. Curr Eye Res. 1990;9:129–138.
  • Lachmann PJ, Hobart MJ. Complement technology. In: Weir DM. Handbook of Experimental Immunology, Ox-ford, England: Blackwell Scientific Publications; 1978:5A.1-5A.23.
  • Matsumoto M, Fukuda W, Circolo A, Goellner J, Strauss-Schoenberger J, Wang X, Fujita S, Hidvegi T, Chaplin DD, Colten HR. Abrogation of the alternative comple-ment pathway by targeted deletion of murine factor B. Proc Natl Acad Sci USA. 1997;94:8720–8725.
  • Klerx JPAM, Beukelman CJ, Van Dijk H, Willers JMN. Microassay for colorimetric estimation of complement activity in guinea pig, human and mouse serum. J Immunol Meth 1983;63: 215–220.
  • Badenoch PR, Finlay-Jones JJ, Coster DJ. Enzymatic disaggregation of the infected rat cornea. Invest Ophthalmol Vis Sci. 1983;24:253–257.
  • Tsai WC, Strieter RM, Zisman DA, Wilkowski JM, Bucknell KA, Chen G-H, Standiford TJ. Nitric oxide is required for effective innate immunity against Klebsiella pneumoniae. Infect Immun. 1997;65:1870–1875.
  • Mello SB, Farsky SH, Sannomiya P, Garcia-Leme J. Inhibition of neutrophil chemotaxis and chemokinesis as-sociated with a plasma protein in aging rats:selective de-pression of cell responses mediated by complement-de-rived chemoattractants. J Leukoc Biol. 1992;51:46–52.
  • Polignano A, Tortorella C, Venezia A, Jirillo E, Antonaci S. Age-associated changes in neutrophil responsiveness in a human healthy elderly population. Cytobios 1994;80:145–153.
  • Mathy—Hartert M, Deby-Dupont G, Melin P, Lamy M, Deby C. Bactericidal activity against Pseudomonas aeru-ginosa is acquired by cultured human monocyte-derived macrophages after uptake of myeloperoxidase. Expe-rientia 1996;52:167–174.

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