14
Views
19
CrossRef citations to date
0
Altmetric
Research Article

Oxidation enhances calpain-induced turbidity in young rat lenses

, , &
Pages 33-40 | Published online: 02 Jul 2009

References

  • Croall DE, DeMartino GN. Calcium-activated neutral protease (Calpain) system: structure, function and regu-lation. Physiol. Rev. 1991;71:813–847.
  • Ma H, Fukiage C, Azuma M, Shearer TR. Cloning and expression of mRNA for calpain Lp82 from rat lens: Splice variant of p94. Invest. Ophthalmol. Vis. Sci. 1998;39:454–461.
  • Shearer TR, Ma H, Fukiage C, Azuma M. Selenite nuclearcataract: review of the model. Mo/. Vis. 1997;3:8.
  • Shearer TR, Shih M, Azuma M, David LL. Precipita-tion of crystallins from young rat lens by endogenous calpain. Exp. Eye Res. 1995;61:141–150.
  • Fukiage C, Azuma M, Nakamura Y, Tamada Y, Shearer TR. Calpain-induced light scattering by crystallins from three rodent species. Exp. Eye Res. 1997;65:757–770.
  • Shearer TR, Shih M, Mizuno T, David LL. Crystallins from rat lens are especially susceptible to calpain-in-duced light scattering compared to other species. Curr. Eye Res. 1996;15:860–868.
  • Fukiage C, Azuma M, Nakamura Y, Tamada Y, Shearer TR. Nuclear cataract and light scattering in cultured lenses from guinea pig and rabbit. Curr. Eye Res. 1998;17:623–635.
  • Spector A. The search for a solution to senile cataracts. Invest. Ophthalmol. Vis. Sci. 1984;25:130–146.
  • Augusteyn RC. Protein modifications in cataract: pos-sible oxidative mechanism. In Mechanisms of cataract Formation in the Human Lens (Duncan, G., ed.) Pp 72–115, Academic Press, London, 1981.
  • Takemoto U. BetaA3/A1 crystallin from human cata-ractous lens contains an intramolecular disulfide bond. Curr. Eye Res. 1997;16:719–724.
  • Takemoto U. Disulfide bond formation of cysteine-37 and cysteine-66 of betaB2 crystallin during cataracto-genesis of the human lens. Exp. Eye Res. 1997;64:609–614.
  • Azuma M, Shearer TR. Involvement of calpain in dia-mide-induced cataract in cultured lenses. FEBS Lett. 1992;307:313–317.
  • Cotlier E. The lens. Adler's Physiology of the Eye. St Louis: C.V. Mosby 1981:277–303.
  • Reddy VN. Dynamics of transport systems in the eye. Invest. Ophthalmol. Vis. Sci. 1979;18:1000–1018.
  • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227:680–685.
  • Towbin H, Steahelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. (USA) 1979;76:4350–4354.
  • Schagger H, Jagow GV. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 1987;166:368–379.
  • Azuma M, Fukiage C, David LL, Shearer TR. Activa-tion of calpain in lens: A review and proposed mecha-nism. Exp. Eye Res. 1997;64:529–538.
  • Azuma M, David LL, Shearer TR. Superior prevention of calcium ionophore cataract by E64d. Biochim. Biophys. Acta. 1992;1180:215–220.
  • Wang KKW, Nath R, Posner A, Raser KJ, Buroker-Kilgore M, Hajimohammadreza I, Probert Jr AW, Marcoux FW, Ye Q, Takano E, Hatanaka M, Maki M, Caner H, Collins JL, Fergus A, Lee KS, Lunney EA, Hay SJ, Yuen P-w. An alpha-mercaptoaccrylic acid de-rivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective. Proc. Natl. Acad. Sci. USA 1996;93:6687–6692.
  • Kosower NS, Kosower EM. Diamide: an oxidant probe for thiols. Methods Enzymol. 1995;251:123–133.
  • Babizhayev MA, Menshikova EV. Diamide-induced cross-linking of the lens water-soluble proteins as a model of the early oxidative changes during senile cataract for-mation. Mech. Ageing Dev. 1990;56:199–208.
  • Lampi KJ, Ma Z, Hanson SR, Azuma M, Shih M, Shearer TR, Smith DL, Smith JB, David LL. Age-related changes in human lens crystallins identified by two-dimensional electrophoresis and mass spectrometry. Exp Eye Res 1998;67(1):31–43.
  • Ma Z, Hanson SR, Lampi KJ, David LL, Smith DL, Smith JB. Age-related changes in human lens crystallins identified by HPLC and mass spectrometry. Exp Eye Res 1998;67 (1): 21–30.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.