Expression of glutamate transporter subtypes in cultured retinal pigment epithelial and retinoblastoma cells

References

• Rauen T. Diversity of glutamate transporter expression and function in the mammalian retina. Amino Acids.2000;19:53–62.
   PubMed Web of Science ®Google Scholar
• Choi DW. Excitotoxic cell death. J NeurobioL1992;23: 1261–1276.
   PubMedGoogle Scholar
• Gegelashvili G, Robinson MB, Troth D, Rauen T. Regula-tion of glutamate transporters in health and disease. Prog Brain Res.2001;132:267–286.
   PubMedGoogle Scholar
• Danbolt NC. Glutamate uptake. Prog NeurobioL2001;65:1–105.
   PubMed Web of Science ®Google Scholar
• Gegelashvili G, Schousboe A. Cellular distribution and kinetic properties of high-affinity glutamate transporters. Brain Res Bull.1998;45:233–238.
   PubMedGoogle Scholar
• Rauen T. Diversity of glutamate transporter expression and function in the mammalian retina. Amino Acids.2000;19: 53–62.
   PubMed Web of Science ®Google Scholar
• Marmor MF. Structure, function and disease of the retinalpigment epithelium. In: Marmor MF, Wolfensberger TJ, eds. The Retinal Pigment Epithelium.1st edn. New York: Oxford University Press; 1998:3–9.
   Google Scholar
• Miyamoto Y, Del Monte MA. Na-dependent glutamate transporter in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci.1994;35:3589–3598.
   PubMed Web of Science ®Google Scholar
• Mäenpää H, Marmerström M, Toimela T, Salminen L, Saransaari P, Tähti H. Glutamate uptake is inhibited by tamoxifen and toremifene in cultured retinal pigment epithelial cells. Pharmacol ToxicoL2002;91:116–122.
   PubMedGoogle Scholar
• Dreyer EB, Zurakowski D, Schumer RA, Podos SM, Lipton SA. Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol.1996;114:299–305.
   Google Scholar
• Naskar R, Vorwerk CK, Dreyer EB. Concurrent downreg-ulation of a glutamate transporter and receptor in glaucoma. Invest Ophthalmol Vis Sci.2000;41:1940–1944.
   PubMed Web of Science ®Google Scholar
• Li Q, Puro DG. Diabetes-induced dysfunction of the gluta-mate transporter in retinal Muller cells. Invest Ophthalmol Vis Sci.2002;43:3109–3116.
   PubMed Web of Science ®Google Scholar
• Marc RE, Murry RIP, Fisher SK, Linberg KA, Lewis GP. Amino acid signatures in the detached cat retina. Invest Ophthalmol Vis Sci.1998;39:1694–1702.
   PubMed Web of Science ®Google Scholar
• Pastor JC, del, Martin F. Proliferative vitreoretinopathy: Risk factors and pathobiology. Prog Retin Eye Res.2002;21:127–144.
   PubMed Web of Science ®Google Scholar
• Stroeva OG, Mitashov VI. Retinal pigment epithelium: Proliferation and differentiation during development and regeneration. Int Rev CytoL1983;83:221–293.
   PubMedGoogle Scholar
• Grierson I, Hiscott P, Hogg P, Robey H, Mazure A, Larkin G. Development, repair and regeneration of the retinal pigment epithelium. Eye.1994;8(Pt 2):255–262.
   PubMedGoogle Scholar
• Pavlidis NA, Petris C, Briassoulis E, Klouvas G, Psilas C, Rempapis J, Petroutsos G. Clear evidence that long-term, low-dose tamoxifen treatment can induce ocular toxicity. A prospective study of 63 patients. Cancer1992;69: 2961–2964.
   Google Scholar
• Alwitry A, Gardner I. Tamoxifen maculopathy. Arch Ophthalmol.2002;120:1402–1402.
   PubMedGoogle Scholar
• Davis AA, Bernstein PS, Bok D, Turner J, Nachtigal M, Hunt RC. A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged culture. Invest Ophthalmol Vis Sci.1995;36:955–964.
   PubMed Web of Science ®Google Scholar
• Gegelashvili G, Dehries Y, Danbolt NC, Schousboe A. The high-affinity glutamate transporters GLT1, GLAST, and EAAT4 are regulated via different signalling mechanisms. Neurochem Int.2000;37:163–170.
   PubMed Web of Science ®Google Scholar
• Mannerström M, Zorn-Kruppa M, Diehl H, Engelke M, Toimela T, Mäenpää H, Huhtala A, Uusitalo H, Salminen L, Pappas P, Marselos M, Mäntylä M, Mäntylä E, Tähti H. Evaluation of the cytotoxicity of selected systemic and intravitreally dosed drugs in the cultures of human retinal pigment epithelial cell line and of pig primary retinal pigment epithelial cells. Toxicol in Vitro.2002;16:193–200.
   PubMedGoogle Scholar
• Bridges CC, Kekuda R, Wang H, Prasad PD, Mehta P, Huang W, Smith SB. Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci.2001;42:47–54.
   Google Scholar
• Derouiche A, Rauen T. Coincidence of L-glutamate/L-aspartate transporter (GLAST) and glutamine synthetase (GS) immunoreactions in retinal glia: Evidence for cou-pling of GLAST and GS in transmitter clearance. J Neu-rosci Res.1995;42:131–143.
   PubMed Web of Science ®Google Scholar
• Lehre KP, Davanger S, Danbolt NC. Localization of the glutamate transporter protein GLAST in rat retina. Brain Res.1997;744:129–137.
   Google Scholar
• Otori Y, Shimada S, Tanaka K, Ishimoto I, Tano Y, Tohyama M. Marked increase in glutamate-aspartate transporter (GLAST/G1uT-1) mRNA following transient retinal ischemia. Brain Res Mol Brain Res.1994;27:310–314.
   PubMedGoogle Scholar
• Kyritsis AP, Tsokos M, Triche TJ, Chader GJ. Retinoblas-toma: A primitive tumor with multipotential characteristics. Invest Ophthalmol Vis Sci.1986;27:1760–1764.
   PubMed Web of Science ®Google Scholar
• Ganel R, Crosson CE. Modulation of human glutamate transporter activity by phorbol ester. J Neurochem.1998; 70:993–1000.
   PubMedGoogle Scholar
• Gegelashvili G, Danbolt NC, Schousboe A. Neuronal soluble factors differentially regulate the expression of the GLT1 and GLAST glutamate transporters in cultured astroglia. J Neurochem.1997;69: 2612–2615.
   Google Scholar
• Plachez C, Danbolt NC, Recasens M. Transient expression of the glial glutamate transporters GLAST and GLT in hippocampal neurons in primary culture. J Neurosci Res.2000;59:587–593.
   Google Scholar
• Pow DV. Amino acids and their transporters in the retina. Neurochem Int.2001;38:463–484.
   PubMedGoogle Scholar
• Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM. ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res.1996;62:155–169.
   PubMed Web of Science ®Google Scholar
• Hiscott P, Sheridan CM. The retinal pigment epithelium, epiretinal membrane formation, and proliferative vitreo-retinopathy. In: Marmor MF, Wolfensberger TJ, eds. The Retinal Pigment Epithelium.1st edn. New York: Oxford University Press; 1998:478–491.
   Google Scholar
• Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP, Amara SG. An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature.1995;375:599–603.
   Google Scholar
• Gegelashvili G, Danbolt NC, Dehnes Y, Balazs R, Cribbs DH, Cotman CW, Rodriguez-Kern A, Gegelashvili M. Caspase-dependent regulation and receptor-like properties of glutamate transporters. Society for Neuroscience Abstracts.2002;441:16.
   Google Scholar
• Jackson M, Song W, Liu MY, Jin L, Dykes H, Lin CI, Bowers WJ, Federoff HJ, Sternweis PC, Rothstein JD. Mod-ulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Nature.2001;410:89–93.
   PubMed Web of Science ®Google Scholar
• Soroceanu L, Manning TJ, Sontheimer H. Modulation of glioma cell migration and invasion using Cl- and IC ion channel blockers. J Neurosci.1999;19:5942–5954.
   Google Scholar
• Mäenpää H, Saransaari P, Tähti H. Kinetics of inhibition of glutamate uptake by antioestrogens. Pharmacol ToxicoL2003;92:in press.
   Google Scholar
• Cyr M, Thibault C, Morissette M, Landry M, Di P Estrogen-like activity of tamoxifen and raloxifene on NMDA receptor binding and expression of its subunits in rat brain. Neuropsychopharmacology.2001;25:242–257.
   PubMedGoogle Scholar
• Freund WD, Grieshop B, Neumann U, Reddig S. Glutamate-induced calcium responses in rat primary corti-cal cultures are potentiated by co-administration of gluta-mate transport inhibitors. Neurosci Lett.1995;188:61–64.
   PubMedGoogle Scholar
• Engelke M, Tykhonova S, Zorn K, Diehl H. Tamoxifen induces changes in the lipid composition of the retinal pigment epithelium cell line d407. Pharmacol ToxicoL2002;91:13–21.
   PubMedGoogle Scholar
• Phillis JW, Song D, Regan MH. Tamoxifen, a chloride channel blocker, reduces glutamate and aspartate release from the ischemic cerebral cortex. Brain Res.1998;780: 352–355.
   Google Scholar
• Zhang JJ, Jacob TJ, Valverde MA, Hardy SP, Mintenig GM, Sepulveda FV, Gill DR, Hyde SC, Trezise AE, Higgins CE Tamoxifen blocks chloride channels. A possible mechanism for cataract formation. J Clin Invest.1994;94:1690–1697.
   PubMed Web of Science ®Google Scholar
• Butchbach ME, Guo H, Lin CL. Methyl-beta-cyclodextrin but not retinoic acid reduces EAAT3-mediated glutamate uptake and increases GTRAP3-18 expression. J Neu-rochem.2003;84: 891–894.
   Google Scholar
• Janssen JJ, Kuhlmann ED, van Vugt AH, Winkens HJ, Janssen BP, Deutman AF, Driessen CA. Retinoic acid delays transcription of human retinal pigment neuroepithe-lium marker genes in ARPE-19 cells. Neuroreport.2000; 11:1571–1579.
   Google Scholar
• Campochiaro PA, Hackett SF, Conway BP. Retinoic acid promotes density-dependent growth arrest in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci.1991;32:65–72.
   Google Scholar
• Chen S, Samuel W, Fariss RN, Duncan T, Kutty RK, Wiggert B. Differentiation of human retinal pigment epithelial cells into neuronal phenotype by N-(4-hydrox-yphenyl)retinamide. J Neurochem.2003;84:972–981.
   PubMed Web of Science ®Google Scholar