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Research Article

Participation of pigment epithelium in ocular immune privilege. 3. Epithelia cultured from iris, ciliary body, and retina suppress T-cell activation by partially non-overlapping mechanisms

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Pages 91-105 | Published online: 08 Jul 2009

References

  • Streilein JW. Regional immunity and ocular immune privilege. In: Streilein JW, editor. Immune response and the eye. Basel: S. Karger, 1999;11–38.
  • Taylor AW. Ocular immunosuppressive microenvironment. In: Streilein JW, editor. Immune response and the eye. Basel: S. Karger, 1999;72–89.
  • Helbig H, Kittredge K, Coca-Prados M, Davis J, Palestine AG, Nussenblatt RB. Mammalian ciliary body epithelial cells in culture produce transforming growth factor-beta. Graefes Arch Clin Exp Ophthalmol. 1991;229:84–87.
  • Streilein JW, Bradley D. Analysis of immunosuppressive properties of iris and ciliary body cells and their secretory products. Invest Ophthalmol Vis Sci. 1991;32:2700–2710.
  • Wilbanks GA, Mammolenti MM, Streilein JW. Studies on the induction of anterior chamber-associated immune deviation (ACAID). III. Induction of ACAID depends upon intraocular transforming growth factor-13. Eur J Immunol. 1992;22: 165–173.
  • Helbig H, Gurley RC, Palestine AG, Nussenblatt RB, Caspi RR. Dual effect of ciliary body cells on T lymphocyte proliferation. Eur J Immunol. 1990;20:2457-2463. 7 Streilein JW, Cousins S, Bradley D. Effect of intraocular gamma-interferon on immunoregulatory properties of iris and ciliary body cells. Invest Ophthalmol Vis Sci. 1992;33: 2304–2315.
  • Yoshida M, Takeuchi M, Streilein JW. Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. I. Inhibition of T cell activation in vitro by direct cell contact. Invest Ophthalmol Vis Sci. 2000:41:811–812.
  • Yoshida M, Kezuka T, Streilein JW. Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 2. Generation of regulatory T cells that suppress bystander T cells via TGF13. Invest Ophthalmol Vis Sci. 2000;41: 3862–3870.
  • Liversidge J, McKay G, Mullen G, Forrester JR. Retinal pigment epithelial cells modulate lymphocyte function at the blood-retina barrier by autocrine PGE2 and membrane-bound mechanisms. Cell Immunol. 1993;149:315–330.
  • Porier F, Robertson EJ. Normal development of mice carrying a null mutation in the gene encoding the L14 S-type lectin. Development. 1993;19:1229–1236.
  • Cooper DN, Massa SM, Barondes SH. Endogenous muscle lectin inhibits myoblast adhesion to laminin. J Cell Biol. 1991;115:1437–1448.
  • Tanihara H, Yoshida M, Matsumoto M, Yoshimura N. Identification of transforming growth factor-beta expressed in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1993;34:413–419.
  • Jorgenson A, Wiencke AK, La Cour M. Human retinal pigment epithelial cell-induced apoptosis in activated T cells. Invest Ophthalmol Vis Sci. 1998;39:1590–1599.
  • Farrokh-Siar L, Rezai KA, Semnani RT, Patel SC, Ernest JT, van Seventer GA. Human fetal retinal pigment epithelial cells induce apoptosis in the T cell line Jurkat.Invest Ophthalmol Vis Sci. 1999;40: 1503–1511.
  • Panjwani N, Jaison PL, Cooper DNVV. Corneal epithelial injury induces expression of galectins in underlying keratocytes (Abstract). Invest Ophthalmol Vis Sci. 1999;40: 3275.
  • Jaison PL, Cooper DNVV, Yang N, Cao Z, Panjwani N. The role of galectins in corneal epithelial wound healing (Abstract). Invest Ophthalmol Vis Sci. 1999;40: 1011.
  • Maldonado CA, Castagna LF, Rabinovich GA, Landa CA. Immunocytochemical study of the distribution of a 16-kDa galectin in the chicken retina. Invest Ophthalmol Vis Sci. 199940: 2971–2979.
  • Uehara F, Ohba N, Ozawa M. Isolation and characterization of galectins in the mammalian retina. Invest Ophthalmol Vis Sci. 2001;42: 2164–2172.
  • Pace KE, Lee C, Stewart PL, Baum LG. Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin- 1. J Immunol. 1999;163:3801-381 I.
  • Perillo NL, Marcus ME, Baum LG. Galectins: versatile modulators of cell adhesion, cell proliferation, and cell death. J Mol Med. 1998;76402–4.12.
  • Kaltner H, Stierstorfer B. Animal lectins as cell adhesion molecules. Acta Anat (Basel). 1998;161:162–179.
  • Zanetta JP. Structure and functions of lectins in the central and peripheral nervous system. Acta Anat (Basel). 1998;161:180–195.
  • Van den Brute FA, Fernandez PL, Buicu C, Liu FT, Jackers P, Lambotte R, Castronova V. Differential expression of galectin-r and galectin-3 during first trimester human embryogenesis. Dev Dyn. 1997;209:399–405.
  • Kasper M, Hughes RC. Immunocytochemical evidence for a modulation of galectin-3 (Mac-2), a carbohydrate binding protein, in pulmonary fibrosis. J PathoL 1996; 179:309–316.
  • Sotomayor CE, Rabinovich GA. Galectin-r induces central and peripheral cell death: implications in T cell physiopathology. Dev Immunol. 2000;7: 117–129.
  • Penninger JM, Irie-Sasaki T, Oliveira-dos-Santos AJ. CD45: new jobs for an old acquaintance. Nat Immunol. 2001;2:389–396.
  • Chung CD, Patel VP, Moran M, Lewis LA, Carrie Miceli M. Galectin- i induces partial TCR zeta-chain phosphorylation and antagonizes processive TCR signal transduction. J Immunol. 2000;165:3722–3729.
  • Blaser C, Kaufmann M, Muller C, Zimmermann C, Wells V, Mallucci L, Pircher H. Beta-galactoside-binding protein secreted by activated T cells inhibits antigen-induced proliferation of T cells. Eur J Immunol. 1998;28:23 11–2319.
  • Liversidge J, Dawson R, Hoey S, McKay D, Grabowski P, Forrester JV. CD59 and CD48 expressed by rat retinal pigment epithelial cells are major ligands for the CD2-mediated alternative pathway of T cell activation. J Immunol. 1996;156: 3696–3703.
  • Holtkamp GM, Kijlstra A, Peek R, de Vos AF. Retinal pigment epithelium-immune system interactions: cytokine production and cytokine-induced changes. Prog Retin Eye Res. 2001;20:29–48.
  • Caspi RR, Roberge FG, Nussenblatt RB. Organ-resident, nonlymphoid cells suppress proliferation of autoimmune T helper lymphocytes. Science. 1987;237:1029-103 I.
  • Kawashima H, Prasad SA, Gregerson DS. Corneal endothelial cells inhibit T cell proliferation by blocking IL-2 production. J Immunol. 1994;153: 1982–1990.

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