Diagnostic classification of autoantibody repertoires in endocrine ophthalmopathy using an artificial neural network

References

• Wall JR. Autoimmunity in Graves' ophthalmopathy. In: Gorman C, Waller R, Dyer J, editors. The Eye and Orbit in Thyroid Disease. New York: Raven Press, 1984; 103–119.
   Google Scholar
• Akman A, Baker JR, Weetman AP, Wartofsky L, Nutman TB, Burman KD. Antibodies to porcine eye muscle in patients with Graves' ophthalmopathy: identification of serum immunoglobulins directed against unique determinants by immunoblotting and enzyme linked immunosorbent assay. J Clin Endocrinol Metab 1989;64:454–460.
   Web of Science ®Google Scholar
• Faryna M, Nauman J, Gardas A. Measurement of autoantibodies against human eye muscle plasma membranes in Graves' ophthalmopathy. Br Med J 1985;290:191–192.
   Google Scholar
• Kendall-Taylor P, Arkinson S, Hocombe M. A specific IgG in Graves' ophthalmopathy and its reaction in retroorbital and thyroid autoimmunity. Br Med J 1985;288:1183–1186.
   Google Scholar
• Kodama K, Sikorska H, Bandy-Danfoe P, Bayly R, Wall JR. Demonstration of a circulating autoantibody against soluble eye muscle antigen in Graves' ophthalmopathy. Lancet 1982;H:1353–1356.
   Google Scholar
• Mengistu M, Laryea E, Miller A, Wall JR. Clinical significance of a new autoantibody against a human eye muscle soluble antigen detected by immunofluorescence. Clin Exp Immunol 1986;65:19–27.
   PubMed Web of Science ®Google Scholar
• Moncayo R, Scherbaum W, Bemetz U, Loos U, Seif F. ELISA systems for the detection of eye muscle and TSH antibodies in Graves' disease with ophthalmopathy. Acta Endocrinol 1985;108(Suppl 267):85–86.
   Google Scholar
• Chang TC, Huang KM, Chang TJ, Lin SL. Correlation of orbital computed tomography and antibodies in patients with hyperthyroid Graves' disease. Clin Endocrinol 199o;32:551–558.
   Google Scholar
• Avarameas S. Natural autoantibodies: from 'horror autotoxicus' to `gnothi seauton'. Immunol Today 1991;12:154–159.
   PubMedGoogle Scholar
• Zimmermann CW, Weiss G. Anti-bodies not directed against the ace-tylcholine receptor in myasthenia gravis: an immunoblot study. J Im-munol 1987;16:225–236.
   Google Scholar
• Zimmermann CW. Repertoires of natural autoantibodies against muscle tissue are independent of age or gender in normal human adults. A Western blot study. Clin Chim Acta 1993;218:29–38.
   PubMed Web of Science ®Google Scholar
• Haury M, Grandien A, Sundblad A, Coutinho A, Nobrega A. Global analysis of antibody repertoires. An immunoblot method for the quantitiative screening of a large number of reactivities. Scand J Immunol 1994;39:79–87.
   Google Scholar
• Zimmermann CW, Grus FH, Dux R. Multivariate statistical comparison of autoantibody repertoires (Western blots) by discriminant analysis. Electrophoresis 1995;16:941–947.
   Google Scholar
• Zimmermann CW, Grus FH, Dux R. Examination of complex autoantibody patterns by discriminance analysis. Med Genet 1993;5:327.
   Google Scholar
• Hebb DO. The Organisation of Be-haviour. New York: Wiley, 1949.
   Google Scholar
• Lashley KD. In search of the engram. In: Society of Experimental Biology Symposium, No. 4. Psychological Mechanism in Animal Behaviour. Cambridge: Cambridge University Press, 1950; 454–480.
   Google Scholar
• Werner SC. Classification of the eye changes of Graves' disease (editorial). J Clin Endocrinol Metab 1969;29:982.
   PubMed Web of Science ®Google Scholar
• Bartalena L, Marcocci C, Bogazzi F, et al. A new ophthalmopathy index for quantitation of eye changes of Graves disease. Acta Endocrinol 1989;12(Suppl 2):190.
   Google Scholar
• Grus FH, Augustin AJ, Toth-Sagi K, Spitzhas M, Roggenkaemper P. Analysis of the human IgG autoantibody repertoire in endocrine ophthalmopathy. Vision Res 1996;32:207.
   Google Scholar
• Laemmli UK. Cleavage of structural proteins during the assembly of head of bacteriophage T4. Nature 1970;227:680–685.
   PubMed Web of Science ®Google Scholar
• Towbin H, Staehlin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitro-cellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979;76:4350–4353.
   Google Scholar
• Grus FH, Nuske JH. Densitometrie mit dem EPSON Scanner GT-6000. In: Schemel-Trumpfheller CK, editor. GIT-Laborjahrbuch 1991. Darmstadt: GIT Verlag, 1991; 234–235.
   Google Scholar
• Nuske JH, Grus FH. Moderne densi-tometrie. BioTec 1993;2:33–35.
   Google Scholar
• Nuske JH, Grus FH. Quantitative densitometrie. BIOForum 1993;11:436–437.
   Google Scholar
• Grus FH, Augustin AJ, Koch F, Zimmermann CW, Lutz J. Autoantibody repertoires in animals with lens-induced uveitis after different therapies using megablot technique: a comparison. Adv Ther 1996;13(4):203–215.
   Google Scholar
• Grus FH. Ein schnelles und einfaches Verfahren zur Analyse komplexer Autoantikörper-Muster. Dissertation Universität-Gesamthochschule Essen, 1994.
   Google Scholar
• Rumelhart DE, Hinton GE, Williams J. Learning representations by backpropagating procedures. Nature 1986;323(6188):533–536.
   Google Scholar
• Meisel W. Computer-oriented Approaches to Pattern Recognition. New York: Academic Press, 1972.
   Google Scholar
• Specht D. Probalistic neural networks. Neural Networks 1990;3:109–118.
   Web of Science ®Google Scholar
• Masters T. Advanced Algorithms for Neural Networks. A C++ Source Book. New York: John Wiley and Sons, Inc., 1995.
   Google Scholar
• Kiljanski JI, Nebes V, Wall JR. The ocular muscle cell is a target of the immune system in endocrine ophthalmopathy. Int Arch Allergy Immunol 1995;106(3):204–212.
   Google Scholar
• Salvi M, Miller A, Wall JR. Human orbital tissue and thyroid membranes express 64 kDa protein which is recognized by autoantibodies in the serum of patients with thyroid-associated ophthalmopathy. Fed Eur Biochem Soc 1988;232: 135–139.
   Google Scholar
• Bernard NR, Nygen TN, Tyutyunikov A, Stolarski C, Scalise D, Genovese C, Hayes MB, Ludgate M, Wall JR. Antibodies against 1 D, a recombinant 64 kDa membrane protein, are associated with ophthalmopathy in patients with thyroid autoimmunity. Clin Immunol Immunopathol 1994;70(3):225–233.
   Google Scholar