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Pharmaceutical Biology Volume 40, 2002 - Issue 1
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Research Article

Effect of Methoxsalen and an Infusion of Silybum marianum on Enzymes Relevant to Liver Function

Aleksandar Raskovic Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine; Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Novi Sad, Yugoslavia
,
Vida Jakovljevic Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine; Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Novi Sad, Yugoslavia
,
Mira Popovic Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine; Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Novi Sad, Yugoslavia
,
Ana Sabo Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine; Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Novi Sad, Yugoslavia
&
Olivera Piljevic Department of Pharmacology, Toxicology and Clinical Pharmacology, Faculty of Medicine; Institute of Chemistry, Faculty of Sciences, University of Novi Sad, Novi Sad, Yugoslavia
Pages 70-73 | Published online: 29 Sep 2008

References

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  • Fouin-Fortunet H, Tinel M, Descatoire V, Letteron Ph, Laney D, Geneve J, Pessayre D (1986): Inactivation of cytochrome P450 by the drug methoxsalen. J Pharmacol Exp Ther 236: 237–242.
  • JakovljeviC V, Ragkovie A, Popovie M, Sabo J, Bursae M (in press): The effect of methoxsalen on hypnotic and subhypnotic doses of pentobarbital. Eur Drug Metabol Pharmacok
  • Kapetanovie IM, Mieyal 11 (1979): Inhibition of acetaminophen induced hepatotoxicity by phenacetin and its alkoxy analogs. J Pharmacol Exp Ther 209: 25–30.
  • List PH, Horhammer TJ (1979): Hagers Handbuch der Phar-mazeutischen Praxis, IV Ausg. Springer Verlag, Berlin.
  • Matsubara T, Baron J, Peterson LL, Peterson JA (1976): Quan-titative determination of cytochrome P450 in rat liver homogenate. Anal Biochem 75: 596–603.
  • Strubelt O, Siegers C, Yames M (1980): The influence of silybin on the hepatotoxic and hypoglycemic effect of prasedymium and others lantanides. Arqneim Forsch 30: 1690–1695.
  • Tallarida RJ, Muray RB (1986): Manual of Pharmacologic Calculations with Computer Programs, 2nd edn. Springer Verlag, New York, pp. 131–134.
  • Tucakov J (1990): Healing with Herbs. Rad, Beograd (in Serbian).
  • Valenzuela A, Aspillaga M, Vial S, Guerrera R (1989): Selec-tivity of silymarin on the increase of the glutathione content in different tissue of the rat. Planta Med 55: 420–422.

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