Triamcinolone acetonide protects auditory hair cells from 4-hydroxy-2,3-nonenal (HNE) ototoxicity in vitro

References

• Flavin MP. Influence of dexamethasone on neurotoxicity caused by oxygen and glucose deprivation in vitro. Exp Neurol 1996; 139: 34–8.
   PubMed Web of Science ®Google Scholar
• Golde S, Coles A, Lindquist JA, Compston A. Decreased iNOS synthesis mediates dexamethasone-induced protection of neurons from inflammatory injury in vitro. Eur J Neurosci 2003; 18: 2527–37.
   PubMed Web of Science ®Google Scholar
• Limbourg FP, Huang Z, Plumier JC, Simoneini T, Fujioka M, Tukerman J, et al. Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids. J Clin Invest 2002; 110: 1729–38.
   PubMed Web of Science ®Google Scholar
• Parnes LS, Sun A-H, Freeman DJ. Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application. Otol Neurotol 1999; 109: 1–17.
   Google Scholar
• Kopke RD, Hoffer ME, Webster D, O'Leary MJ, Jackson RL. Targeted topical steroid therapy in sudden sensorineural hearing loss. Otol Neurotol 2001; 22: 475–9.
   PubMed Web of Science ®Google Scholar
• Plontke S, Lowenheim H, Preyer S, Liens P, Dietz K, Koitschev A, et al. Outcomes research analysis of continuous intratympanic glucocorticoid delivered in patients with acute severe to profound hearing loss: basis for planning randomized controlled trials. Acta Otolaryngol (Stockh) 2005; 125: 830–9.
   PubMed Web of Science ®Google Scholar
• Zuo J, Curtis LM. Glucocorticoid receptor expression in the postnatal rat cochlea. Hear Res 1995; 87: 220–7.
   PubMed Web of Science ®Google Scholar
• Rarey KE, Curtis LM. Receptors for glucocorticoids in the human inner ear. Otolaryngol Head Neck Surg 1996; 115: 38–41.
   PubMed Web of Science ®Google Scholar
• Rarey KE, Gerhardt KJ, Curtis LM, ten Cate WJ. Effect of stress on cochlear glucocorticoid protein: acoustic stress. Hear Res 1995; 82: 135–8.
   PubMed Web of Science ®Google Scholar
• Terunuma T, Kawauchi S, Kajihara M, Takahashi S, Hara A. Effect of acoustic stress on glucocorticoid receptor mRNA in the cochlea of the guinea pig. Brain Res Mol Brain Res 2003; 120: 65–72.
   PubMedGoogle Scholar
• Mori T, Fujimura K, Yoshida M, Suzuki H. Effects of glucocorticoid receptor antagonist on CAPs threshold shift due to short-term sound exposure in guinea pigs. Auris Nasus Larynx 2004; 31: 395–9.
   PubMed Web of Science ®Google Scholar
• de Ceulaer G, Johnson S, Yperman M, Daemers K, Officiers FE, O'Donoghue GM, et al. Long-term evaluation of the effect of intracochlear steroid deposition on electrode impedance in cochlear implant patients. Otol Neurotol 2003; 24: 769–74.
   PubMed Web of Science ®Google Scholar
• Oddera S, Cagnoni F, Mangraviti S, Giron-Michel J, Popova O, Canonica GW. Effect of triamcinolone acetonide on adult human lung fibroblasts: decrease in proliferation, surface molecule expression and mediator release. Int Arch Allergy Immunol 2002; 129: 152–9.
   PubMed Web of Science ®Google Scholar
• Scarpidis U, Madnani D, Shoemaker C, Fletcher CH, Kojima K, Eshraghi AA, et al. Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantation. Otol Neurotol 2003; 24: 409–17.
   PubMed Web of Science ®Google Scholar
• Yamashita D, Jiang H-Y, Schacht J, Miller JM. Delayed production of free radicals following noise exposure. Brain Res 2004; 1019: 201–9.
   PubMed Web of Science ®Google Scholar
• Massin P, Audren F, Haouchine B, Erginay A, Bergmann J-F, Benosman R, et al. Intravitreal triamcinolone acetonide for diabetic diffuse macular edema. Ophthalmology 2004; 111: 218–25.
   PubMed Web of Science ®Google Scholar
• McCloskey SE, Gershanik JJ, Lertora JJL, White L, George WJ. Toxicity of benzyl alcohol in adult and neonatal mice. J Pharm Sci 1986; 75: 702–5.
   PubMed Web of Science ®Google Scholar
• Yoritaka A, Hattori N, Uchida K, Tanaka M, Stadtman ER, Mizuno Y. Immunohistochemical detection of 4-hydroxy- 2,3-nonenal protein adducts in Parkinson's disease. Proc Natl Acad Sci USA 1996; 93: 2696–700.
   PubMed Web of Science ®Google Scholar
• Chandrasekhar SS, Rubenstein RY, Kwartler JA, Gatz M, Connelly PE, Huang E, et al. Dexamethasone pharmoki-netics in the inner ear: comparison of route of administration and use of facilitating agents. Otolaryngol Head Neck Surg 2000; 122: 521–8.
   PubMed Web of Science ®Google Scholar
• Kiefer J, Gstottner W, Baumgartner W, Pok SM, Tillein J, Ye Q, et al. Conservation of low frequency hearing in cochlear implantation. Acta Otolaryngol (Stockh) 2004; 124: 272–80.
   PubMed Web of Science ®Google Scholar
• Kopke RD, Liu W, Gabaizadeh R, Jacono A, Feghali J, Spray D, et al. Use of organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatinindeced damage of auditory hair cells. Am J Otol 1997; 18: 559–71.
   PubMedGoogle Scholar
• Hu BH, Henderson D, Nicotera TM. Involvement of apoptosis in progression of cochlear lesion following exposure to intense noise. Hear Res 2002; 166: 62–71.
   PubMed Web of Science ®Google Scholar
• Eshraghi AA, Polak M, He J, Telischi FF, Balkany TJ, Van De Water TR. Pattern of hearing loss in a rat model of cochlear implantation trauma. Otol Neurotol 2005; 26: 442–7.
   PubMed Web of Science ®Google Scholar
• Wang J, Van De Water TR, Bonny C, de Ribaupierre F, Puel J-L, Zine A. A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory cells death and hearing loss. J Neurosci 2003; 23: 8596–607.
   PubMed Web of Science ®Google Scholar
• Ma W, Gee K, Lim W, Chambers K, Angel JB, Kozlowski M, et al. Dexamethasone inhibits IL-12p40 production in lipopolysaccharide-stimulated human monocytic cells by down-regulating the activity of c-Jun N-terminal kinase, the activation protein-1, and NFkB transcription factors. J Immunol 2004; 172: 318–30.
   PubMed Web of Science ®Google Scholar
• Song BJ, Soh Y, Bae M-A, Pie J-E, Wan J, Jeong K-S. Apoptosis of PC 12 cells by 4-hydroxy-2-nonenal is mediated through selective activation of the c-Jun N-terminal kinase pathway. Chem Biol Interact 2001; 130–132: 943–54.
   PubMed Web of Science ®Google Scholar
• Himeno C, Komeda M, Izumikawa M, Takemura K, Yagi M, Weiping Y, et al. Intra-cochlear administration of dexamethasone attenuates aminoglycoside ototoxicity in the guinea pig. Hear Res 2002; 167: 61–70.
   PubMed Web of Science ®Google Scholar
• Takemura K, Komeda M, Yagi M, Himeno C, Izumikawa M, Doi T, et al. Direct inner ear infusion of dexamethasone attenuates noise-induced trauma in guinea pig. Hear Res 2004; 196: 58–68.
   PubMed Web of Science ®Google Scholar
• Almeida OF, Conde GL, Crochemore C, Demenix BA, Fisher D, Hassan AH, et al. Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate. FASEB J 2000; 14: 779–90.
   PubMed Web of Science ®Google Scholar
• Charalampopoulos I, Tsatsanis C, Dermitzaki E, Alexaki VI, Castana T, Margolis AN, et al. Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins. Proc Natl Acad Sci USA 2004; 101: 8209–14.
   PubMed Web of Science ®Google Scholar